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Preferentially increased nitration of α-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson’s disease
α-Synuclein is a major component of Lewy bodies, proteinacious inclusions which are a major hallmark of Parkinson’s disease (PD). Lewy bodies contain high levels of nitrated tyrosine residues as determined by antibodies specific for 3-nitrotyrosine (3NT) and via mass spectrometry (MS). We have devel...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748813/ https://ncbi.nlm.nih.gov/pubmed/19697948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901176t |
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