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Quantitative Mapping of Reversible Mitochondrial Complex I Cysteine Oxidation in a Parkinson Disease Mouse Model

Differential cysteine oxidation within mitochondrial Complex I has been quantified in an in vivo oxidative stress model of Parkinson disease. We developed a strategy that incorporates rapid and efficient immunoaffinity purification of Complex I followed by differential alkylation and quantitative de...

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Main Authors: Danielson, Steven R., Held, Jason M., Oo, May, Riley, Rebeccah, Gibson, Bradford W., Andersen, Julie K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045014/
https://ncbi.nlm.nih.gov/pubmed/21196577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190108
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