Dual targeting of EphA2 and FAK in ovarian carcinoma

EphA2 gene silencing has been shown to result in anti-tumor efficacy. Here we considered whether silencing additional targets downstream of EphA2 would further enhance the therapeutic effect. EphA2 targeted siRNA was tested in combination with either FAK or Src targeted siRNA using DOPC nanoliposome...

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Autori principali: Shahzad, Mian M.K., Lu, Chunhua, Lee, Jeong-Won, Stone, Rebecca L., Mitra, Rahul, Mangala, Lingegowda S., Lu, Yiling, Baggerly, Keith A., Danes, Christopher G., Nick, Alpa M., Halder, Jyotsnabaran, Kim, Hye-Sun, Vivas-Mejia, Pablo, Landen, Charles N., Lopez-Berestein, Gabriel, Coleman, Robert L., Sood, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748749/
https://ncbi.nlm.nih.gov/pubmed/19395869
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