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Design of protein-interaction specificity affords selective bZIP-binding peptides

Interaction specificity is a required feature of biological networks and a necessary characteristic of protein or small-molecule reagents and therapeutics. The ability to alter or inhibit protein interactions selectively would advance basic and applied molecular science. Assessing or modelling inter...

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Autori principali: Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748673/
https://ncbi.nlm.nih.gov/pubmed/19370028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07885
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