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Carbon-Deuterium Bonds as Probes of Dihydrofolate Reductase
Much effort has been directed towards understanding the contributions of electrostatics and dynamics to protein function and especially to enzyme catalysis. Unfortunately, these studies have been limited by the absence of direct experimental probes. We have been developing the use of carbon-deuteriu...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748670/ https://ncbi.nlm.nih.gov/pubmed/18412341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0779607 |
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