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CO-OPERATION BETWEEN MOLECULAR TARGETS OF COSTIMULATION IN PROMOTING T CELL PERSISTENCE AND TUMOR REGRESSION
Costimulation regulates multiple cellular processes of T cells inducing proliferation, expansion and survival. The molecular targets of costimulation might then be useful to augment T cell activities. Two defined targets of costimulatory signals in primary T cells are the anti-apoptotic bcl-2 family...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748393/ https://ncbi.nlm.nih.gov/pubmed/19454669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804387 |
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