CO-OPERATION BETWEEN MOLECULAR TARGETS OF COSTIMULATION IN PROMOTING T CELL PERSISTENCE AND TUMOR REGRESSION

Costimulation regulates multiple cellular processes of T cells inducing proliferation, expansion and survival. The molecular targets of costimulation might then be useful to augment T cell activities. Two defined targets of costimulatory signals in primary T cells are the anti-apoptotic bcl-2 family...

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Hlavní autoři: Zhao, Baohua, Song, Aihua, Haque, Rizwanul, Lei, Fengyang, Weiler, Lauren, Xiong, Xiaofang, Wu, Yuzhang, Croft, Michael, Song, Jianxun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748393/
https://ncbi.nlm.nih.gov/pubmed/19454669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804387
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