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FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development

INTRODUCTION: Forkhead box p3 (FoxP3)-expressing regulatory T cells (Tregs) have been clearly implicated in the control of autoimmune disease in murine models. In addition, ectopic expression of FoxP3 conveys a Treg phenotype to CD4(+ )T cells, lending itself to therapeutic use in the prevention of...

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保存先:
書誌詳細
主要な著者: Haque, Rizwanul, Lei, Fengyang, Xiong, Xiaofang, Wu, Yuzhang, Song, Jianxun
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888221/
https://ncbi.nlm.nih.gov/pubmed/20384988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2983
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