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FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development
INTRODUCTION: Forkhead box p3 (FoxP3)-expressing regulatory T cells (Tregs) have been clearly implicated in the control of autoimmune disease in murine models. In addition, ectopic expression of FoxP3 conveys a Treg phenotype to CD4(+ )T cells, lending itself to therapeutic use in the prevention of...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888221/ https://ncbi.nlm.nih.gov/pubmed/20384988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2983 |
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