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Systematic Study of the Genetic Response of a Variable Virus to the Introduction of Deleterious Mutations in a Functional Capsid Region

We have targeted the intersubunit interfaces in the capsid of foot-and-mouth disease virus to investigate the genetic response of a variable virus when individual deleterious mutations are systematically introduced along a functionally defined region of its genome. We had previously found that the i...

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Detalhes bibliográficos
Main Authors: Luna, Eva, Rodríguez-Huete, Alicia, Rincón, Verónica, Mateo, Roberto, Mateu, Mauricio G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748030/
https://ncbi.nlm.nih.gov/pubmed/19625409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00903-09
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