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Expected Effect of Deleterious Mutations on Within-Host Adaptation of Pathogens
Adaptation is a common theme in both pathogen emergence, for example, in zoonotic cross-species transmission, and pathogen control, where adaptation might limit the effect of the immune response and antiviral treatment. When such evolution requires deleterious intermediate mutations, fitness ridges...
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| Publicado no: | J Virol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542389/ https://ncbi.nlm.nih.gov/pubmed/26109724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00832-15 |
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