Thermostability of the Foot-and-Mouth Disease Virus Capsid Is Modulated by Lethal and Viability-Restoring Compensatory Amino Acid Substitutions

Infection by viruses depends on a balance between capsid stability and dynamics. This study investigated biologically and biotechnologically relevant aspects of the relationship in foot-and-mouth disease virus (FMDV) between capsid structure and thermostability and between thermostability and infect...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: López-Argüello, Silvia, Rincón, Verónica, Rodríguez-Huete, Alicia, Martínez-Salas, Encarnación, Belsham, Graham J., Valbuena, Alejandro, Mateu, Mauricio G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498042/
https://ncbi.nlm.nih.gov/pubmed/30867300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02293-18
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