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High avidity autoreactive CD4(+) T cells induce host CTL, overcome T(regs) and mediate tumor destruction
Despite progress made over the past 25 years, existing immunotherapies have limited clinical effectiveness in patients with cancer. Immune tolerance consistently blunts the generated immune response, and the largely solitary focus on CD8(+) T cell immunity has proven ineffective in the absence of CD...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747815/ https://ncbi.nlm.nih.gov/pubmed/19561540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181ab1824 |
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