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Propofol Activates and Allosterically Modulates Recombinant Protein Kinase Cε
BACKGROUND: Myocardial protection by anesthetics is known to involve activation of protein kinase C epsilon (PKCε). A key step in the activation process is auto-phosphorylation of the enzyme at serine 729. Our objectives were to identify the extent to which propofol interacts with PKCε and to identi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747769/ https://ncbi.nlm.nih.gov/pubmed/19512879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181a3274b |
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