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Propofol Restores Transient Receptor Potential Vanilloid Receptor Subtype-1 Sensitivity via Activation of Transient Receptor Potential Ankyrin Receptor Subtype-1 in Sensory Neurons

BACKGROUND: Crosstalk between peripheral nociceptors belonging to the transient receptor potential vanilloid receptor subtype-1 (TRPV1) and ankyrin subtype-1 (TRPA1) family has recently been demonstrated. Moreover, the intravenous anesthetic propofol has been shown to directly activate TRPA1 recepto...

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Detalhes bibliográficos
Main Authors: Zhang, Hongyu, Wickley, Peter J., Sinha, Sayantani, Bratz, Ian N., Damron, Derek S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085581/
https://ncbi.nlm.nih.gov/pubmed/21364461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31820dee67
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