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Protein Kinase Cε Modulates Insulin Receptor Localization and Trafficking in Mouse Embryonic Fibroblasts

We have previously shown that deletion of protein kinase C epsilon (PKCε) in mice results in protection against glucose intolerance caused by a high fat diet. This was in part due to reduced insulin uptake by hepatocytes and insulin clearance, which enhanced insulin availability. Here we employed mo...

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Detalhes bibliográficos
Main Authors: Pedersen, David J., Diakanastasis, Barbara, Stöckli, Jacqueline, Schmitz-Peiffer, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585804/
https://ncbi.nlm.nih.gov/pubmed/23469261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058046
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