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THE CALCITRIOL ANALOGUE EB1089 IMPAIRS ALVEOLARIZATION AND INDUCES LOCALIZED REGIONS OF INCREASED FIBROBLAST DENSITY IN NEONATAL RAT LUNG

The active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) (1,25-(OH)(2)D(3), or calcitriol), is a potent mitogen for fibroblasts cultured from rat lungs at postnatal day 4 (P4), during the peak of septation (P3 to P7). In light of the key role of fibroblasts in alveolar septation, the authors cond...

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Bibliographische Detailangaben
Hauptverfasser: Ormerod, Angela K., Xing, Zhenlan, Pedigo, Nancy G., Mishra, Anjali, Kaetzel, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747600/
https://ncbi.nlm.nih.gov/pubmed/18432454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01902140801929325
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