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EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro

1. Effects of the synthetic vitamin D analogue EB1089 on indices of apoptosis in cultured human breast cancer cells and in nitrosomethylurea-induced rat mammary tumours in vivo were investigated. 2. At a dose of 0.5 μg kg(−1) body weight, EB1089 caused significant inhibition of tumour progression ov...

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Main Authors: James, Sharon Y, Mercer, Elizabeth, Brady, Matthew, Binderup, Lise, Colston, Kay W
格式: Artigo
語言:Inglês
出版: 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565659/
https://ncbi.nlm.nih.gov/pubmed/9846632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702103
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