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A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo.

We have examined the effects of 1,25 dihydroxyvitamin D3 (1,25[OH]2D3) and a low calcemic analogue EB1089 on parathyroid hormone-related peptide (PTHRP) production and on the development of hypercalcemia in Fischer rats implanted with the Leydig cell tumor H-500. Leydig cell tumors were implanted su...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Haq, M, Kremer, R, Goltzman, D, Rabbani, S A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8514854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116475
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