Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines

In the treatment of breast cancer, combination chemotherapy is used to overcome drug resistance. Combining doxorubicin and vinorelbine in the treatment of patients with metastatic breast cancer has shown high response rates; even single-agent vinorelbine in patients previously exposed to anthracycli...

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Autors principals: Liem, A A, Appleyard, M V C L, O'Neill, M A, Hupp, T R, Chamberlain, M P, Thompson, A M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747573/
https://ncbi.nlm.nih.gov/pubmed/12698197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600898
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