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Identification of Quinolines that Inhibit Melanogenesis by Altering Tyrosinase Family Trafficking
A series of quinolines, including chloroquine and quinine, were identified as potent pigmentation inhibitors through screening a compound library in murine melanocytes. Structure-activity relationship analysis indicated that 4-substituted amino groups with a tertiary amine side chain, such as chloro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747315/ https://ncbi.nlm.nih.gov/pubmed/18801917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.050633 |
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