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Mechanical Membrane Injury Induces Axonal Beading through Localized Activation of Calpain

Diffuse axonal injury (DAI), a major component of traumatic brain injury, is characterized by a sequence of neurochemical reactions initiated at the time of trauma and resulting in axonal degeneration and cell death. Calcium influx through mechanically induced axolemmal pores and subsequent activati...

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Autors principals: Kilinc, Devrim, Gallo, Gianluca, Barbee, Kenneth A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747288/
https://ncbi.nlm.nih.gov/pubmed/19619536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.07.014
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