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5-Cyanotryptophan as an Infrared Probe of Local Hydration Status of Proteins

The nitrile (C≡N) stretching vibration is sensitive to environment, making nitrile-derivatized amino acids an increasingly utilized tool to study various biological processes. Herein, we show that the bandwidth of the C≡N stretching vibration of 5-cyanotryptophan is particularly sensitive to water,...

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Autors principals: Waegele, Matthias M., Tucker, Matthew J., Gai, Feng
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747115/
https://ncbi.nlm.nih.gov/pubmed/20161057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cplett.2009.07.058
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