A Nasal Proteosome Adjuvant Activates Microglia and Prevents Amyloid Deposition

OBJECTIVE: We assessed whether peripheral activation of microglia by a nasal proteosome-based adjuvant (Protollin) that has been given safely to humans can prevent amyloid deposition in young mice and affect amyloid deposition and memory function in old mice with a large amyloid load. METHODS: Amylo...

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Bibliografiset tiedot
Päätekijät: Frenkel, Dan, Puckett, Lindsay, Petrovic, Sanja, Xia, Weiming, Chen, Guiquan, Vega, Jose, Dembinsky-Vaknin, Adi, Shen, Jie, Plante, Martin, Burt, David S., Weiner, Howard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747093/
https://ncbi.nlm.nih.gov/pubmed/18360829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21340
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