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Misfolded proteins partition between two distinct quality control compartments
The accumulation of misfolded proteins in intracellular amyloid inclusions, typical of many neurodegenerative disorders including Huntington's and prion disease, is thought to occur after failure of the cellular protein quality control mechanisms. Here we examine the formation of misfolded prot...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746971/ https://ncbi.nlm.nih.gov/pubmed/18756251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07195 |
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