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Talin depletion reveals independence of initial cell spreading from integrin activation and traction
Cell spreading, adhesion and remodelling of the extracellular matrix (eCM) involve bi-directional signalling and physical linkages between the eCM, integrins and the cell cytoskeleton1–3. the actin-binding proteins talin1 and 2 link ligand-bound integrins to the actin cytoskeleton and increase the a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746969/ https://ncbi.nlm.nih.gov/pubmed/19160486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1765 |
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