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Inhibition of Gelatinase Activity Reduces Neural Injury in an Ex-Vivo Model of Hypoxia-Ischemia

Perinatal hypoxia-ischemia (H-I) often manifests as cognitive and/or motor disturbances that appear early in development. Growing evidence indicates that neuroinflammation may exacerbate H-I injury. Resident microglia release proinflammatory cytokines and proteases in response to ischemia. Matrix me...

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Detalhes bibliográficos
Main Authors: Leonardo, Christopher C., Hall, Aaron A., Collier, Lisa A., Gottschall, Paul E., Pennypacker, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746919/
https://ncbi.nlm.nih.gov/pubmed/19272421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.02.080
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