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COX-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractility

Pulmonary arterial hypertension (PAH) is a significant disease process characterized by elevated pulmonary vascular resistance leading to increased right ventricular afterload and ultimately progressing to right ventricular dysfunction and often death. Irreversible remodeling of the pulmonary vascul...

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Detalhes bibliográficos
Main Authors: Fredenburgh, Laura E., Ma, Jun, Perrella, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746907/
https://ncbi.nlm.nih.gov/pubmed/19577709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.04.003
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