Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) is an Ischemia-inducible Secreted Endoplasmic Reticulum (ER) Stress Response Protein in the Heart

The endoplasmic reticulum (ER) stress response (ERSR) is activated when folding of nascent proteins in the ER lumen is impeded. Myocardial ischemia was recently shown to activate the ERSR; however, the role of this complex signaling system in the heart is not well understood. ER stress activates the...

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Bibliografiske detaljer
Main Authors: Tadimalla, Archana, Belmont, Peter J., Thuerauf, Donna J., Glassy, Matthew S., Martindale, Joshua J., Gude, Natalie, Sussman, Mark A., Glembotski, Christopher C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746824/
https://ncbi.nlm.nih.gov/pubmed/18927462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.180679
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