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Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology and therapeutic roles
Mesencephalic astrocyte-derived neurotrophic factor (MANF), a newly identified 18 kDa soluble protein, localizes to the luminal endoplasmic reticulum (ER). ER stress can stimulate MANF expression and secretion. In Drosophila and zebrafish, MANF regulates dopaminergic neuron development. In contrast,...
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| Publicado no: | Transl Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601018/ https://ncbi.nlm.nih.gov/pubmed/28719799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.06.010 |
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