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Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology and therapeutic roles
Mesencephalic astrocyte-derived neurotrophic factor (MANF), a newly identified 18 kDa soluble protein, localizes to the luminal endoplasmic reticulum (ER). ER stress can stimulate MANF expression and secretion. In Drosophila and zebrafish, MANF regulates dopaminergic neuron development. In contrast,...
Gardado en:
| Publicado en: | Transl Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601018/ https://ncbi.nlm.nih.gov/pubmed/28719799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.06.010 |
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