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Safety and immunologic effects of IL-15 administration in nonhuman primates
The administration of cytokines that modulate endogenous or transferred T-cell immunity could improve current approaches to clinical immunotherapy. Interleukin-2 (IL-2) is used most commonly for this purpose, but causes systemic toxicity and preferentially drives the expansion of CD4(+)CD25(+)Foxp3(...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746471/ https://ncbi.nlm.nih.gov/pubmed/19605850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-189266 |
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