Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

Interleukin-15 (IL-15) is a cytokine with potential therapeutic application in individuals with cancer or immunodeficiency to promote natural killer (NK)– and T-cell activation and proliferation or in vaccination protocols to generate long-lived memory T cells. Here we report that 10-50 μg/kg IL-15...

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Main Authors: Lugli, Enrico, Goldman, Carolyn K., Perera, Liyanage P., Smedley, Jeremy, Pung, Rhonda, Yovandich, Jason L., Creekmore, Stephen P., Waldmann, Thomas A., Roederer, Mario
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Immunobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995354/
https://ncbi.nlm.nih.gov/pubmed/20631381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-275438
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