Safety and immunologic effects of IL-15 administration in nonhuman primates

The administration of cytokines that modulate endogenous or transferred T-cell immunity could improve current approaches to clinical immunotherapy. Interleukin-2 (IL-2) is used most commonly for this purpose, but causes systemic toxicity and preferentially drives the expansion of CD4(+)CD25(+)Foxp3(...

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Detaylı Bibliyografya
Asıl Yazarlar: Berger, Carolina, Berger, Michael, Hackman, Robert C., Gough, Michael, Elliott, Carole, Jensen, Michael C., Riddell, Stanley R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2009
Konular:
Immunobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746471/
https://ncbi.nlm.nih.gov/pubmed/19605850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-189266
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