Llwytho...

Parasites bearing a single copy of the multi-drug resistance gene (pfmdr-1) with wild-type SNPs predominate amongst Plasmodium falciparum isolates from Malawi

We genotyped 160 P. falciparum infections from Malawi for pfmdr-1 copy number changes and SNPs associated with in vivo tolerance and poor in vitro sensitivity to the component drugs of Coartem. We also measured in vitro susceptibility of 49 of these isolates to a variety of drugs in clinical use or...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nkhoma, Standwell, Nair, Shalini, Mukaka, Mavuto, Molyneux, Malcolm E., Ward, Stephen A., Anderson, Timothy J.C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746100/
https://ncbi.nlm.nih.gov/pubmed/19426667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actatropica.2009.01.011
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