Mice Lacking Brain/Kidney Phosphate-Activated Glutaminase Have Impaired Glutamatergic Synaptic Transmission, Altered Breathing, Disorganized Goal-Directed Behavior and Die Shortly after Birth

Neurotransmitter glutamate has been thought to derive mainly from glutamine via the action of glutaminase type 1 (GLS1). To address the importance of this pathway in glutamatergic transmission, we knocked out GLS1 in mice. The insertion of a STOP cassette by homologous recombination produced a null...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Masson, Justine, Darmon, Michèle, Conjard, Agnès, Chuhma, Nao, Ropert, Nicole, Thoby-Brisson, Muriel, Foutz, Arthur S., Parrot, Sandrine, Miller, Gretchen M., Jorisch, Renée, Polan, Jonathan, Hamon, Michel, Hen, René, Rayport, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745954/
https://ncbi.nlm.nih.gov/pubmed/16641247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4241-05.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados