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Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice

Genetic pharmacotherapy is an early drug development strategy for the identification of novel CNS targets in mouse models prior to the development of specific ligands. Here for the first time, we have implemented this strategy to address the potential therapeutic value of a glutamate-based pharmacot...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Syst Neurosci
Päätekijät: Mingote, Susana, Masson, Justine, Gellman, Celia, Thomsen, Gretchen M., Lin, Chyuan-Sheng, Merker, Robert J., Gaisler-Salomon, Inna, Wang, Yvonne, Ernst, Rachel, Hen, René, Rayport, Stephen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705219/
https://ncbi.nlm.nih.gov/pubmed/26778975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2015.00165
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