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Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Human T-cell leukemia virus type I (HTLV-I) is the etiological agent of adult T-cell leukemia (ATL). Our recent studies have shown that one important mechanism of HTLV-I-Mediated tumorigenesis is through PDZ-LIM domain-containing protein 2 (PDLIM2) repression, although the involved mechanism remains...

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Hlavní autoři: Yan, Pengrong, Qu, Zhaoxia, Ishikawa, Chie, Mori, Naoki, Xiao, Gutian
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745669/
https://ncbi.nlm.nih.gov/pubmed/19794962
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