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Delaying BCG vaccination from birth to 10 weeks of age may result in an enhanced memory CD4 T cell response

BACKGROUND: In most tuberculosis (TB) endemic countries, bacillus Calmette Guérin (BCG) is usually given around birth to prevent severe TB in infants. The neonatal immune system is immature. Our hypothesis was that delaying BCG vaccination from birth to 10 weeks of age would enhance the vaccine-indu...

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Detalhes bibliográficos
Main Authors: Kagina, Benjamin M. N., Abel, Brian, Bowmaker, Mark, Scriba, Thomas J., Gelderbloem, Sebastian, Smit, Erica, Erasmus, Mzwandile, Nene, Nonhlanhla, Walzl, Gerhard, Black, Gillian, Hussey, Gregory D., Hesseling, Anneke C., Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745558/
https://ncbi.nlm.nih.gov/pubmed/19616494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.103
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