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Irradiation alters selection for oncogenic mutations in hematopoietic progenitors

Exposure to ionizing radiation and other DNA damaging carcinogens is strongly associated with induction of malignancies. Prevailing paradigms attribute this association to the induction of oncogenic mutations, as the incidence of oncogenic events is thought to limit initiation and progression of can...

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Detalhes bibliográficos
Main Authors: Marusyk, Andriy, Casás-Selves, Matias, Henry, Curtis J., Zaberezhnyy, Vadym, Klawitter, Jelena, Christians, Uwe, DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745506/
https://ncbi.nlm.nih.gov/pubmed/19738065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0604
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