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Irradiation alters selection for oncogenic mutations in hematopoietic progenitors

Exposure to ionizing radiation and other DNA damaging carcinogens is strongly associated with induction of malignancies. Prevailing paradigms attribute this association to the induction of oncogenic mutations, as the incidence of oncogenic events is thought to limit initiation and progression of can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marusyk, Andriy, Casás-Selves, Matias, Henry, Curtis J., Zaberezhnyy, Vadym, Klawitter, Jelena, Christians, Uwe, DeGregori, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745506/
https://ncbi.nlm.nih.gov/pubmed/19738065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0604
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