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Design and Evaluation of New Analogs of the Sweet Protein Brazzein

We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than w...

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Detalhes bibliográficos
Main Authors: Walters, D. Eric, Cragin, Tiffany, Jin, Zheyuan, Rumbley, Jon N., Hellekant, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745351/
https://ncbi.nlm.nih.gov/pubmed/19696120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bjp048
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