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Cortical Injury Increases Cholesterol 24S Hydroxylase (Cyp46) Levels in the Rat Brain

In traumatic brain injury (TBI), cellular loss from initial impact as well as secondary neurodegeneration leads to increased cholesterol and lipid debris at the site of injury. Cholesterol accumulation in the periphery can trigger inflammatory mechanisms while cholesterol clearance may be anti-infla...

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Main Authors: Cartagena, Casandra M., Ahmed, Farid, Burns, Mark P., Pajoohesh-Ganji, Ahdeah, Pak, Daniel T., Faden, Alan I., Rebeck, G. William
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745316/
https://ncbi.nlm.nih.gov/pubmed/18729719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2007.0444
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