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Inhibition of C-Jun N-Terminal Kinase Increases ApoE Expression In Vitro and In Vivo
Apolipoprotein E (apoE), a ligand for the low-density lipoprotein (LDL) receptor family, has been implicated in modulating glial inflammatory responses and the risk of neurodegeneration associated with Alzheimer’s disease. Glial cells activated by lipopolysaccharide (LPS) have decreased apoE levels...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745314/ https://ncbi.nlm.nih.gov/pubmed/19615334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.048 |
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