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Inhibition of C-Jun N-Terminal Kinase Increases ApoE Expression In Vitro and In Vivo

Apolipoprotein E (apoE), a ligand for the low-density lipoprotein (LDL) receptor family, has been implicated in modulating glial inflammatory responses and the risk of neurodegeneration associated with Alzheimer’s disease. Glial cells activated by lipopolysaccharide (LPS) have decreased apoE levels...

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Main Authors: Pocivavsek, Ana, Rebeck, G. William
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745314/
https://ncbi.nlm.nih.gov/pubmed/19615334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.048
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