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Inhibition of C-Jun N-Terminal Kinase Increases ApoE Expression In Vitro and In Vivo

Apolipoprotein E (apoE), a ligand for the low-density lipoprotein (LDL) receptor family, has been implicated in modulating glial inflammatory responses and the risk of neurodegeneration associated with Alzheimer’s disease. Glial cells activated by lipopolysaccharide (LPS) have decreased apoE levels...

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Bibliografiske detaljer
Main Authors: Pocivavsek, Ana, Rebeck, G. William
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745314/
https://ncbi.nlm.nih.gov/pubmed/19615334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.048
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