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Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
Mutations in PINK1 and parkin cause autosomal recessive parkinsonism, a neurodegenerative disorder characterized by the loss of dopaminergic neurons. To highlight potential therapeutic pathways we have identified factors that genetically interact with parkin/PINK1. Here we report that overexpression...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745154/ https://ncbi.nlm.nih.gov/pubmed/19684592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2372 |
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