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Large scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways

The bacterial pathogen Legionella pneumophila replicates in a specialized vacuole within host cells. Establishment of the replication vacuole depends on the Dot/Icm translocation system that delivers a large number of protein substrates into the host cell. The functions of most substrates are unknow...

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Autori principali: Heidtman, Matthew, Chen, Emy J., Moy, Man-Yu, Isberg, Ralph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744955/
https://ncbi.nlm.nih.gov/pubmed/19016775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01249.x
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