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Interferon-β treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1

Interferon-β is a current treatment for multiple sclerosis (MS). Interferon-β is thought to exert its therapeutic effects on MS by down-modulating the immune response by multiple potential pathways. Here, we document that treatment of MS patients with interferon β-1a (Rebif) results in a significant...

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Détails bibliographiques
Auteurs principaux: Christophi, George P., Panos, Michael, Hudson, Chad A., Tsikkou, Chriso, Mihai, Cornelia, Mejico, Luis J., Jubelt, Burk, Massa, Paul T.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744840/
https://ncbi.nlm.nih.gov/pubmed/19559654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.05.019
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