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Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy
Our recent reports indicated that polyploidization of aortic vascular smooth muscle cells (VSMC) serves as a biomarker for aging, and that the polyploid state is linked to a higher incidence of senescence in vivo. Here, we found that NADPH oxidase 4 (Nox4) expression is augmented in VSMC from aortas...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2009
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744814/ https://ncbi.nlm.nih.gov/pubmed/19221493 |
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