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Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

Our recent reports indicated that polyploidization of aortic vascular smooth muscle cells (VSMC) serves as a biomarker for aging, and that the polyploid state is linked to a higher incidence of senescence in vivo. Here, we found that NADPH oxidase 4 (Nox4) expression is augmented in VSMC from aortas...

詳細記述

保存先:
書誌詳細
主要な著者: McCrann, Donald J., Yang, Dan, Chen, Hongjie, Carroll, Shannon, Ravid, Katya
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744814/
https://ncbi.nlm.nih.gov/pubmed/19221493
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