Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane

BACKGROUND: The spread of drug resistance has been a major obstacle to the control of malaria. The mechanisms underlying drug resistance in malaria seem to be complex and multigenic. The current literature on multiple drug resistance against anti-malarials has documented PfMDR1, an ATP-binding casse...

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Main Authors: Kavishe, Reginald A, van den Heuvel, Jeroen MW, van de Vegte-Bolmer, Marga, Luty, Adrian JF, Russel, Frans GM, Koenderink, Jan B
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744701/
https://ncbi.nlm.nih.gov/pubmed/19715599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-205
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