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An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases

Ring-shaped AAA+ ATPases control a variety of cellular processes by substrate unfolding and remodeling of macromolecular structures. However, how ATP hydrolysis within AAA+ rings is regulated and coupled to mechanical work is poorly understood. Here, we demonstrate coordinated ATP hydrolysis within...

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Detalhes bibliográficos
Main Authors: Augustin, Steffen, Gerdes, Florian, Lee, Sukyeong, Tsai, Francis T.F., Langer, Thomas, Tatsuta, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744646/
https://ncbi.nlm.nih.gov/pubmed/19748354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.018
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