Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

Increased intestinal permeability (IP) has emerged recently as a common underlying mechanism in the pathogenesis of allergic, inflammatory, and autoimmune diseases. The characterization of zonulin, the only physiological mediator known to regulate IP reversibly, has remained elusive. Through proteom...

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Main Authors: Tripathi, Amit, Lammers, Karen M., Goldblum, Simeon, Shea-Donohue, Terez, Netzel-Arnett, Sarah, Buzza, Marguerite S., Antalis, Toni M., Vogel, Stefanie N., Zhao, Aiping, Yang, Shiqi, Arrietta, Marie-Claire, Meddings, Jon B., Fasano, Alessio
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744629/
https://ncbi.nlm.nih.gov/pubmed/19805376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906773106
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