Gata1 expression driven by the alternative HS2 enhancer in the spleen rescues the hematopoietic failure induced by the hypomorphic Gata1(low) mutation

Rigorously defined reconstitution assays developed in recent years have allowed recognition of the delicate relationship that exists between hematopoietic stem cells and their niches. This balance ensures that hematopoiesis occurs in the marrow under steady-state conditions. However, during developm...

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Autori principali: Migliaccio, Anna Rita, Martelli, Fabrizio, Verrucci, Maria, Sanchez, Massimo, Valeri, Mauro, Migliaccio, Giovanni, Vannucchi, Alessandro Maria, Zingariello, Maria, Di Baldassarre, Angela, Ghinassi, Barbara, Rana, Rosa Alba, van Hensbergen, Yvette, Fibbe, Willem E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744572/
https://ncbi.nlm.nih.gov/pubmed/19571316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-211680
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