Characterization of the TGF-β1 signaling abnormalities in the Gata1(low) mouse model of myelofibrosis

Primary myelofibrosis (PMF) is characterized by fibrosis, ineffective hematopoiesis in marrow, and hematopoiesis in extramedullary sites and is associated with abnormal megakaryocyte (MK) development and increased transforming growth factor (TGF)-β1 release. To clarify the role of TGF-β1 in the path...

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Detalhes bibliográficos
Main Authors: Zingariello, Maria, Martelli, Fabrizio, Ciaffoni, Fiorella, Masiello, Francesca, Ghinassi, Barbara, D’Amore, Emanuela, Massa, Margherita, Barosi, Giovanni, Sancillo, Laura, Li, Xiaochun, Goldberg, Judith D., Rana, Rosa Alba, Migliaccio, Anna Rita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637011/
https://ncbi.nlm.nih.gov/pubmed/23462118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-439661
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