Lentiviral Transduction of ApoAI Into Hematopoietic Progenitor Cells and Macrophages: Applications to Cell Therapy of Atherosclerosis

OBJECTIVE: We used genetically engineered mouse hematopoietic progenitor cells (HPCs) to investigate the therapeutic effects of human apoAI on atherosclerosis in apoE(−/−) mice. METHODS AND RESULTS: Lentiviral constructs expressing either human apoAI (LV-apoAI) or green fluorescent protein (LV-GFP)...

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Hlavní autoři: Su, Yan Ru, Blakemore, John L., Zhang, Youmin, Linton, MacRae F., Fazio, Sergio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744493/
https://ncbi.nlm.nih.gov/pubmed/18497309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.160093
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